›› 2013, Vol. 15 ›› Issue (2): 28-32.DOI: doi:10.3969/j.issn.1008-0864.2013.02.05

• 组学研究特稿 • 上一篇    下一篇

植物代谢组学应用研究——现状与展望

张凤霞,王国栋*   

  1. (中国科学院遗传与发育生物学研究所, 北京 100101)
  • 收稿日期:2013-02-20 修回日期:2013-03-25 出版日期:2013-04-15 发布日期:2013-04-16
  • 通讯作者: 王国栋,研究员,博士生导师,主要从事植物功能代谢组学研究。Tel: 010-64806572; E-mail: gdwang@genetics.ac.cn
  • 作者简介:张凤霞|博士|研究方向为植物代谢组学分析。Tel: 010-64806573;E-mail: zhangfx@genetics.ac.cn。
  • 基金资助:

    国家973计划项目(2012CB113900)资助。

The Applications of Metabolomics in Plant Biology——Current Status and Prospective

ZHANG Feng-xia, WANG Guo-dong*   

  1. (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China)
  • Received:2013-02-20 Revised:2013-03-25 Online:2013-04-15 Published:2013-04-16

摘要:

植物产生超过20万种代谢物(分子量小于1 000的有机化合物),这些代谢物在植物的生活史中发挥着重要的生理功能。因此,植物代谢组学在现代植物生物学研究及其生物技术应用中发挥着非常重要的作用。通过代谢组学和转录组学数据(或其他组学数据)的关联分析,人们可以更加快速地解析参与代谢网络的基因功能。最近,植物代谢组学在一些新兴的研究领域(如代谢流组学,辅酶因子组学等)也扮演着越来越重要的角色。对作为植物功能基因组学和系统生物学研究工具的代谢组学研究现状与展望做一个概述,以期为了解并研究相关领域提供参考。

关键词: 代谢组学;代谢流组学;辅酶因子组学;系统生物学;基因功能

Abstract:

Plants collectively produce more than 200 000 organic chemicals (molecular weight <1 000), which exhibit diverse physiological functions during the life cycle of plants. Thus, plant metabolomics now plays a fundamental role in plant biology and applied biotechnology. The association analysis of metabolomics and transcriptomics data (or other omics data) is a powerful tool for elucidating the function of genes involved in plant metabolic network. In recent years, plant metabolomics exhibits new potentials to new research fields such as fluxome and cofactome analysis. We briefly discussed the current status and the applications of metabolomics as a plant functional genomics and system biology tool in this review, which was expected to provide a referance for understanding and studing meatbolomics.

Key words: meatbolomics, fluxome, cofactome, system biology, gene function

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