关键词: 猪源大肠杆菌；抗菌药物；耐药；最小抑菌浓度

Abstract:

In order to investigate the drug resistance of Escherichia coli isolated from pig manuer of large\|scale pig farm and local farmers piggeries on commonly used antimicrobial drugs in Baijiantan region of Karamay City, Xinjiang, this experiment conducted test with minimal inhibitory concentrations (MIC) of antimicrobial drugs on these isolates by broth micro\|dilution method. The results showed that 701 Escherichia coli were isolated from 703 fecal samples (including 549 isolates from large\|scale pig farm and 152 isolates from farmers piggeries). The isolated Escherichia coli were highly resistant to ampicillin and amoxicillin / clavulanic by over 77.0%. These isolates were very sensitive to amikacin. Their tolerant rate reached 11.1%. Isolates tolerant to 3 or more than 3 antimicrobial drugs accounted for 17.0%. In this region, the tolerance of pig Escherichia coli to commonly used antimicrobial drugs was very serious, so in clinical treatment of bacterial diseases, the use of insensitive antimicrobial drugs should be avoid. The tolerant rate of Escherichia coli isolated from large\|scale pig farm was lower than that from the farmers piggeries.

Key words: Escherichia coli from pigs, antimicrobial drug, tolerance, minimum inhibitory concentration