关键词: 马鼻狂蝇, 细胞免疫, 体液免疫, 免疫组织化学, 咽部

Abstract: In order to investigate the situation of cellular and humoral immunity infected by Rhinoestrus spp. larva in Mongolian horse, this experiment selected 8 horses infected by Rhinoestrus spp. larva from slaughter house in Hohhot as infected group and 5 healthy horses as the control group. The presence of larvae induced a huge local recruitment of either leucocytes (macrophages) or granulocytes (eosinophils, mast cells). This cellular response was pronounced in the Mongolian horse pharyngeal (development sites of second and third instar larvae). Infected horse produced Rhinoestrus spp. specific IgG antibodies in their mucus and serum. Compared to the control group, the sinusal mucosa of infected animals was extremely thickened and the epithelium exhibited hyperplasia, metaplasia and eosinophilic exocytosis. This experiment initially explored the pathological changes and immunologic mechanism of horse infected by Rhinoestrus spp. larvae.

Key words: Rhinoestrus spp., cellular immunity, humoral immunity, immunohistochemistry, pharyngeal