关键词: 非洲猪瘟病毒, 灭活技术, 诊断技术

Abstract: African swine fever (ASF) is an acute hemorrhagic infectious disease of domestic pigs and wild boar caused by African swine fever virus (ASFV). The World Organization for Animal Health (OIE) lists it as a notifiable animal disease. As there is no effective vaccine against ASF currently, quarantine, culling and strict biosecurity measures are mainly adopted to prevent and control the disease in China. Disinfection is an important means of biosecurity against ASF. At present, there are various inactivation methods for ASFV, but the inactivation effect needs to be further tested. Current ASF etiological diagnostic techniques cannot determine the infectivity of a sample and therefore cannot accurately evaluate the efficacy of a disinfectant against the pathogen. This review summarized the main ASFV disinfection techniques and their mechanisms, killing effect, advantages and disadvantages, and analyzed the problems existing in disinfection technologies and the limitations of the current detection techniques, and further the potential techniques for differential detection of infectious ASFV were discussed to provide references for innovation and improvement of ASFV diagnostic technology and effective control of ASF.

Key words: African swine fever virus, inactivation technology, diagnostic techniques