苯酚羟化酶的功能与调控研究进展

doi:10.3969/j.issn.1008-0864.2010.05.07

›› 2010, Vol. 12 ›› Issue (5): 36-41.DOI: 10.3969/j.issn.1008-0864.2010.05.07

苯酚羟化酶的功能与调控研究进展

彭子欣1,于海英1,2,战嵛华1,陈明1,林敏1,张维1

(1.中国农业科学院生物技术研究所, 北京 100081|2.中国农业大学生物学院, 北京 100193)

收稿日期:2010-05-18 修回日期:2010-05-26 出版日期:2010-10-15 发布日期:2010-08-27
通讯作者: 张维,副研究员,硕士生导师,主要从事极端微生物分子生物学研究。E-mail:zhwmm@caas.net.cn
作者简介:彭子欣,博士研究生,研究方向为微生物基因工程。E-mail:pengzixin1982@163.com。
基金资助:
国家自然科学基金项目(30770076);国家转基因生物新品种培育重大专项(2008ZX08012-001)资助。

Advances in Studying Function and Regulation of |Phenol Hydroxylase

PENG Zi-xin1, YU Hai-ying1,2, ZHAN Yu-hua1, CHEN Ming1, LIN Min1, ZHANG Wei1

(1.Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081|2.College of Biological Sciences, China Agriculture University, Beijing 100193, China)

Received:2010-05-18 Revised:2010-05-26 Online:2010-10-15 Published:2010-08-27

摘要/Abstract

摘要：

苯酚是一种广泛存在的芳香烃污染物,可以被一些环境微生物降解。苯酚好氧降解的第一步是苯酚被苯酚羟化酶催化为邻苯二酚。苯酚羟化酶的转录主要由XylR/DmpR调控蛋白激活,另外在一些多组分苯酚羟化酶操纵子中也发现了起抑制作用的调控蛋白。综述了苯酚降解菌中苯酚羟化酶的功能和调控机制等方面的研究进展。

关键词: 苯酚;苯酚羟化酶;调控蛋白;XylR/DmpR

Abstract:

Phenol is one kind of aromatic contaminants ubiquitously distributed in environment and can be degradated by some microorganisms. The first step of aerobic degradation for phenol-degrading strain is to form catechol catalysed by phenol hydroxylase. The transcription of phenol hydroxylase is mainly activated by XylR/DmpR protein, but some repressive regulators were found in multi-component phenol hydroxylase operons. This paper reviews the research progresses made in studying the function and regulation mechanism of phenol hydroxylase.

Key words: phenol, phenol hydroxylase, modulin, xylR/DmpR

中图分类号:

X172

彭子欣1,于海英1,2,战嵛华1,陈明1,林敏1,张维1. 苯酚羟化酶的功能与调控研究进展[J]. , 2010, 12(5): 36-41.

PENG Zi-xin1, YU Hai-ying1,2, ZHAN Yu-hua1, CHEN Ming1, LIN Min1, ZHANG Wei1. Advances in Studying Function and Regulation of |Phenol Hydroxylase[J]. , 2010, 12(5): 36-41.

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苯酚羟化酶的功能与调控研究进展

Advances in Studying Function and Regulation of |Phenol Hydroxylase

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