转基因植物生产药用蛋白研究进展

›› 2007, Vol. 9 ›› Issue (5): 36-44.

转基因植物生产药用蛋白研究进展

陈玉辉赵凌侠崔丽洁唐克轩

上海交通大学农业与生物学院植物生物技术研究中心,生命科学技术学院,复旦-交大-诺丁汉植物生物技术研发中心,上海200030

收稿日期:2007-05-29 修回日期:2007-07-03 出版日期:2007-10-15 发布日期:2009-10-19
通讯作者: 唐克轩，博士，教授，主要从事植物分子生物学、植物生物反应器等研究。Tel：02162932002；E—mail：kxtangl@yahoo．eom，kxtangl@163．COm
作者简介:陈玉辉|博士研究生|主要从事植物生物反应器研究
基金资助:
国家“863”计划和上海市科学技术委员会资助.

Progress in Transgenic Plants Producing Pharmaceutical Proteins

CHEN Yu-hui, ZHA0 Ling-xia, CUI Li-jie, TANG Ke-xuan

Plant Biotechnology Research Center, School of Agriculture and Biology, School of Life Science and Technology, Fudan-SJTU-Nottingham Plant Biotechnology R＆D Center, Shanghai Jiao Tong University, Shanghai 200030, China

Received:2007-05-29 Revised:2007-07-03 Online:2007-10-15 Published:2009-10-19

摘要/Abstract

摘要：

利用转基因植物作为生物反应器生产具有重要价值的多肽和蛋白质，包括抗体、疫苗、药用蛋白等较之其他系统具有很多优越性，已经成为当前植物基因工程和药物生物技术领域中的研究热点，着重就这一领域近年来国内外的研究现状、发展趋势、存在的问题及对策进行综述。

关键词: 转基因植物药用蛋白生物反应器

Abstract:

The application of transgenic plants as bioreactors in the production of highly valued medical polypeptides and proteins, including antibodies, vaccines and pharmaceutical proteins has many advantages over other production systems, and has become a hot spot in plant genetic engineering and pharmaceutical biotechnology in recent years. The internal and external research progress, development tendency and existing problems in this area were reviewed in this article.

Key words: transgenic plants, pharmaceutical protein, bioreactor

中图分类号:

Q77 TQ93

陈玉辉赵凌侠崔丽洁唐克轩. 转基因植物生产药用蛋白研究进展[J]. , 2007, 9(5): 36-44.

CHEN Yu-hui, ZHA0 Ling-xia, CUI Li-jie, TANG Ke-xuan . Progress in Transgenic Plants Producing Pharmaceutical Proteins[J]. , 2007, 9(5): 36-44.