关键词: 苏云金芽孢杆菌（Bt） 氨肽酶N（APN） 受体 突变 抗性

Abstract:

The use of Cry toxins from Bacillus thuringiensis(Bt) to control insect pests is a revolutionary progress in crop production.Change in binding ability between Bt insecticidal proteins and its receptors may be the main mechanism of Lepidoptera insect resistance to Bt toxin.Aminopeptidase N(APN) is one kind of receptors for Bacillus thuringiensis(Bt) toxin in insect midguts.Through discussing its binding capability with Bt toxin,this paper summarizes the molecular biology mechanism of APN gene and Bt resistan..

Key words: Bacillus thuringiensis（Bt）, aminopeptidase N（APN）, receptor, mutation, resistance;