关键词: 叶酸；对氨基苯甲酸；蝶啶；生物强化

Abstract:

Tetrahydrofolate and its derivatives, commonly grouped under the name of folates, are vital cofactors for enzymes that mediate onecarbon transfer reactions. Folates are involved in a wide range of key metabolic functions. Human cannot synthesize folates de novo and depends entirely on dietary supply. Folate deficiency contributes to many disease risks. Engineering crop plants with elevated folate contents (biofortification) is therefore a rational alternative in addressing global folate deficiency. In the present paper, we summarized the folate metabolism, and progress made in research on folate biofortification. Besides, the folate nutritional status of the Chinese people was summarized and folate biofortification situation in China was prospected.

Key words: tetrahydrofolate(THF), p-ABA, pteridine, biofortification