›› 2009, Vol. 11 ›› Issue (S1): 13-16.

• 重金属检测 • 上一篇    下一篇

基于胸腺嘧啶-汞离子(Ⅱ)配位作用的汞离子(Ⅱ)检测技术的研究进展

刘斯佳1,朱静1,谭钟扬1,2   

  1. (1.湖南大学化学化工学院,化学/生物传感与计量学国家重点实验室, 长沙 410082|2.湖南大学生命科学与技术学院, 长沙 410082)
  • 收稿日期:2009-08-15 修回日期:2009-10-20 出版日期:2009-12-16 发布日期:2009-12-15
  • 通讯作者: 谭钟扬,教授,从事植物病毒分子生物学和生物传感技术研究。E-mail:hunandaxuetzy@163.com
  • 作者简介:刘斯佳,博士研究生,从事生物化学分析研究。Tel:0731-88821916|E-mail:zhongyang@hnu.cn

Research Advances in Detection of Mercury(Ⅱ) based on Thymine-Hg2+ Coordination Chemistry

LIU Si-jia1, ZHU Jing1, TAN Zhong-yang1,2   

  1. (1.State Key Laboratory for Chemo/biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, |Changsha 410082|2. College of Life Science and Technology, Hunan University, Changsha 410082, China)
  • Received:2009-08-15 Revised:2009-10-20 Online:2009-12-16 Published:2009-12-15

摘要:

通过胸腺嘧啶-汞离子(Ⅱ)-胸腺嘧啶(T-Hg2+-T)特异性配位结构的形成,汞离子(Ⅱ)可以稳定寡聚核苷酸中胸腺嘧啶-胸腺嘧啶(T-T)错配杂交,利用这种特殊原理可以高灵敏度、高选择性地检测汞离子(Ⅱ)。探讨了基于该机理的汞离子(Ⅱ)检测技术研究进展,该类技术在实时环境监测方面的应用具有很可观的潜力。

关键词: 环境;汞;分析, T-Hg2+-T配位

Abstract:

Through thymine-Hg2+-thymine (T-Hg2+-T) coordination, the resulting Hg2+-stabilized hybridization of oligonucleotides with T-T mismatches have been demonstrated as sensitive and selective strategies for Hg2+ detection. The paper revealed this Hg2+sensing system, and it was expected to hold considerable potential in on-site applications of Hg2+ detection.

Key words: environment, mercury, analysis, T-Hg2+-T coordination

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