Journal of Agricultural Science and Technology ›› 2019, Vol. 21 ›› Issue (4): 42-51.DOI: 10.13304/j.nykjdb.2018.0335

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Research Progress on Aflatoxin Detoxification

WANG Jingying1, WANG Zhuo2, YAN Peisheng1*   

  1. 1.School of Marine Science and Technology, Harbin Institute of Technology at Weihai, Shandong Weihai 264209; 2.Food Department, Shandong Drug and Food Vocational College, Shandong Weihai 264210, China
  • Received:2018-05-30 Online:2019-04-15 Published:2018-07-26

黄曲霉毒素的脱毒研究进展

王婧莹1,王琢2,闫培生1*   

  1. 1.哈尔滨工业大学(威海)海洋科学与技术学院, 山东 威海 264209; 2.山东药品食品职业学院食品系, 山东 威海 264210
  • 通讯作者: *通信作者:闫培生,教授,博士生导师,主要从事有害微生物的生物防治与食品安全、海洋微生物资源与利用、海洋生物质及其加工废物的高值资源化、微生物发酵工程与生物制药等研究。E-mail:yps6@163.com
  • 作者简介:王婧莹,硕士研究生,主要从事食品安全与生物防控研究。E-mail:wangjingying0721@163.com。
  • 基金资助:
    中国大洋协会项目(DY125-15-R-01);山东省高等学校科技计划项目(J15LE60)资助。

Abstract: Aflatoxin is natural toxin produced by fungi. It can be mainly classified as aflatoxin B, aflatoxin G, and aflatoxin M. To mankind and livestock, aflatoxins have high toxicity, teratogenicity, mutagenicity, and carcinogenicity. Compared to other aflatoxins, aflatoxin B1 is the most toxic. Aflatoxin B1 and aflatoxin M1 have been classified as Group 1 (established carcinogens to human) by International Agency for Research on Cancer. Therefore, how to detoxify aflatoxins has won increasing attention at home and abroad. This paper mainly expounded the physical methods, chemical methods, and biological methods for aflatoxin detoxification at home and abroad, laying emphasis on reviewing the varieties of biological methods for aflatoxin detoxification, detoxification mechanisms, and toxicity of degradation products. Before ending, the paper also prospected the future for research activities in this field.

Key words: aflatoxin, detoxification, physical detoxification method, chemical detoxification method, biological detoxification method

摘要: 黄曲霉毒素是由真菌代谢产生的天然毒素,主要分为B族黄曲霉毒素、G族黄曲霉毒素及M族黄曲霉毒素。黄曲霉毒素对人类和动物具有较高的毒性、致畸性、诱变性和致癌性,其中黄曲霉毒素B1的毒性最高,且黄曲霉毒素B1和黄曲霉毒素M1被国际癌症研究机构列为一级致癌物。因此,黄曲霉毒素的脱毒越来越受到国内外的广泛关注。主要对国内外黄曲霉毒素的物理脱毒方法、化学脱毒方法及生物脱毒方法进行综述,重点对生物脱毒方法的种类、脱毒机理和降解产物的毒性进行了评述,并提出研究展望。

关键词: 黄曲霉毒素, 脱毒, 物理脱毒方法, 化学脱毒方法, 生物脱毒方法