Research Progress on Metabolic Engineering of Escherichia coli Strains for Ethanol Production

›› 2009, Vol. 11 ›› Issue (4): 29-33.

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Research Progress on Metabolic Engineering of Escherichia coli Strains for Ethanol Production

HONG Hao-zhou ¹, MA Rui-qiang ^1,2, ZHANG Ying ¹, LU Wei ¹, ZHANG Wei ¹, CHEN Ming ¹

1.Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081;
2.College of Biological Science, China Agricultural University, Beijing 100193, China

Received:2009-01-20 Revised:2009-03-06 Online:2009-08-15 Published:2009-07-24

产乙醇重组大肠杆菌的研究进展

洪浩舟¹,马瑞强^1,2,张颖¹,陆伟¹,张维¹,陈明¹

1.中国农业科学院生物技术研究所, 北京 100081|2.中国农业大学生物学院, 北京 100193

通讯作者: 陈明，研究员，主要从事环境微生物分子生物学研究。E-mail：chenmingbio@hotmail.com
作者简介:洪浩舟,硕士研究生,研究方向为生物化学与分子生物学。
基金资助:
国家973计划项目(2007CB707805)；国家863计划项目(2006AA02Z229;2006AA010101)资助。

Abstract

Abstract:

Production of bio-ethanol from low cost cellulosic materials by microbes has been paid more attention. Recent research has focused on metabolic engineering and improvement of strains for high ethanol production. Here we presented a brief summary of the research progress made in recombinant Escherichia coli strains for ethanol production. The studies on metabolic engineering improvement taking E. coli as a model strain will provide techniques and reference for the new ethanologenic recombinant strains.

Key words: Escherichia coli, metabolic engineering, ethanol, cellulose

摘要：

利用微生物从低廉的纤维素、半纤维素及其水解产物生产生物燃料乙醇受到高度重视。代谢工程技术构建和改造高产乙醇重组菌成为研究的重点。着重概述了产乙醇重组大肠杆菌的研究进展。以大肠杆菌作为模式菌株进行乙醇代谢工程改造的研究和探索，将为新型的产乙醇重组微生物提供技术依据和借鉴。

关键词: 大肠杆菌, 代谢工程, 乙醇, 纤维素

CLC Number:

S216.3

HONG Hao-zhou, MA Rui-qiang, ZHANG Ying, LU Wei, ZHANG Wei, CHEN Ming. Research Progress on Metabolic Engineering of Escherichia coli Strains for Ethanol Production[J]. , 2009, 11(4): 29-33.

洪浩舟,马瑞强,张颖,陆伟,张维,陈明. 产乙醇重组大肠杆菌的研究进展[J]. , 2009, 11(4): 29-33.

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Research Progress on Metabolic Engineering of Escherichia coli Strains for Ethanol Production

产乙醇重组大肠杆菌的研究进展

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