Progress on Fumagillin and its Application on Apis Nosema Disease Control

doi:10.13304/j.nykjdb.2015.345

Journal of Agricultural Science and Technology ›› 2016, Vol. 18 ›› Issue (2): 52-58.DOI: 10.13304/j.nykjdb.2015.345

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Progress on Fumagillin and its Application on Apis Nosema Disease Control

CAO Wei-rui, XUE Xiao-feng, WU Li-ming*

Institute of Apicultural Research, Chinese Academy of Agricultural Science, Beijing 100093, China

Received:2015-06-16 Online:2016-04-15 Published:2015-09-29

烟曲霉素及其防治蜜蜂微孢子虫病的研究进展

曹葳蕤,薛晓锋,吴黎明*

中国农业科学院蜜蜂研究所, 北京 100093

通讯作者: 吴黎明，研究员，博士生导师，主要从事蜂产品质量安全与控制研究。E-mail：apiswu@126.com
作者简介:曹葳蕤|硕士研究生|主要从事蜂产品质量安全与控制研究。E-mail：hostrawberry@qq.com。
基金资助:
国家自然科学基金项目（31172274）；现代农业（蜂）产业技术体系项目（CARS-45）；中国农业科学院科技创新工程专项（CAAS-ASTIP-2015-IAR）资助。

Abstract

Abstract: Fumagillin is a potent antibiotic isolated from Aspergillus fumigatus. It is widely used in apiculture curing Apis Nosema disease. This paper summarized the research progress made in fumagillin, including its molecular structure, antibiotic theory, toxicity, stability; the usage status in controlling Apis Nosema disease; and the detection methods of fumagillin residue in apiculture products. The paper also prospected the future research directions concerning fumagillin and its application in apiculture industry.

Key words: fumagillin, Apis Nosema disease, research progress

摘要： 烟曲霉素是一种从烟曲霉菌（Aspergillus fumigatus）发酵液中分离出来的抗生素，由于其对微孢子虫高效的抗菌作用，被广泛地应用于养蜂业中治疗蜜蜂微孢子虫（Apis Nosema）病。综述了烟曲霉素的分子结构和性质、应用及作用机制，并介绍了烟曲霉素的毒副作用和检测方法，最后对烟曲霉素相关的研究方向及其在养蜂业中的应用前景进行了展望。

关键词: 烟曲霉素, 蜜蜂微孢子虫, 研究进展

CAO Wei-rui, XUE Xiao-feng, WU Li-ming*. Progress on Fumagillin and its Application on Apis Nosema Disease Control[J]. Journal of Agricultural Science and Technology, 2016, 18(2): 52-58.

曹葳蕤,薛晓锋,吴黎明*. 烟曲霉素及其防治蜜蜂微孢子虫病的研究进展[J]. 中国农业科技导报, 2016, 18(2): 52-58.

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Progress on Fumagillin and its Application on Apis Nosema Disease Control

烟曲霉素及其防治蜜蜂微孢子虫病的研究进展

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