关键词: 基因组编辑, 植物, 安全评价

Abstract: Genome editing technologies have saved the long time period of multi-generation hybridization needed by conventional breeding; thus, speeded up the breeding process. At the same time, there are potential risks due to the artificial increase of mutation efficiency and existence of off-target effects. Herein, this paper brievely reviewed the principles, merits and demerits of the 3 mainly technologies in genome editing; compared them with the conventional breeding method and transgenetic technology, and discussed the advanteges of genome editing techniques and their products and the possible biological safety risks caused by off-target effect. The regulatory models and related policies of genome editing plants in the worlds major countries were also elaborated. Finally, the paper discussed the safety assessment of genome editing technique in China combined with Chinese current regulations on definition of transgenic plants and principles of risk assessment. Before ending, the paper put forward thonghts on managing safety assessment of genome editing plants.

Key words: genome editing, plants, safety assessment