关键词: 优先碳源;碳代谢抑制;调节机制

Abstract:

When exposed to a medium with multi-carbon sources, most bacteria can use one preferred carbon source and prevent the metabolism and utilization of other compounds through decreasing the expression of corresponding genes by repression protein of carbon metabolism. This is called as carbon catabolism repression and widespread in bacteria, which is one of the hotspot of microbe metabolizability research. Through selective utilization of the carbon sources, bacteria obtain high competition and adaptation ability in their living niches. The protein of catabolism repression could play a role through complicated regulation systems, including transcription of activation or repression and control translation of related genes. There are some differences between the class of acting proteins and mechanisms in different bacteria. This review summarized some kind of acting proteins and mechanisms of CRC, which contributed to convince the environment adaption and metabolic diversity and the molecular regulation of carbon metabolism in bacteria.

Key words: preferred carbon sources, carbon catabolism repression control, regulation mechanism