›› 2013, Vol. 15 ›› Issue (5): 53-58.DOI: doi:10.3969/j.issn.10080864.2013.05.08

• 农业微生物制剂与酶产品创制特稿 • 上一篇    下一篇

超氧化物歧化酶(SOD)的应用研究进展

董亮1|何永志2|王远亮1*|董志扬2*   

  1. (1.湖南农业大学食品科技学院| 长沙 410128; 2.中国科学院微生物研究所| 微生物资源前期开发国家重点实验室| 北京 100101)
  • 出版日期:2013-10-15 发布日期:2013-12-16
  • 通讯作者: 王远亮,教授,博士,主要从事食品微生物研究。E\|mail:yuanliangw@gmail.com;董志扬,研究员,博士,主要从事分子酶学研究。E\|mail:dongzy@ im.ac.cn
  • 作者简介:董亮|硕士研究生|研究方向为食品生物技术。E\|mail:donglianglim@163.com。
  • 基金资助:

    国家863计划项目(2007AA100604);微生物资源前期开发国家重点试验室开放课题(SKLMR\|2009060)资助。

Research Progress on Application of Superoxide Dismutase (SOD)

DONG Liang1, HE Yong\|zhi2, WANG Yuan\|liang1*, DONG Zhi\|yang2*   

  1. (1.Institute of Food Science and Technology, Hunan Agricultural University, Changsha 410128; 2.State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China)
  • Online:2013-10-15 Published:2013-12-16

摘要:

超氧化物歧化酶(superoxide dismutase,简称SOD)是一种能够催化超氧化物通过歧化反应转化为氧气和过氧化氢的酶。它广泛存在于各类动物、植物、微生物中,是一种重要的抗氧化剂,保护暴露于氧气中的细胞。近年来,SOD在农业和医药等多个领域都展现出了巨大的应用价值和开发前景。对SOD的功能、抗氧化机制、类型以及生产方式等进行了概述,并重点综述了SOD在工业(医药工业,食品和日化工业)和农业上的的应用情况及发展潜力,以期为我国SOD产品的深入开发和利用提供参考。

关键词: 超氧化物歧化酶;活性氧;自由基;研究进展

Abstract:

Superoxide dismutase (SOD) catalyzes the disproportionation of univalently reduced oxygen to generate oxygen and hydrogen peroxide. SOD has been widely discovered in living organisms, including animals, plants and microorganisms and has been demonstrated to be an important antioxidant, which protects the cells exposed to the toxicity of oxygen. Recently, SOD has displayed huge application value and development prospect. This paper gave an sumarized SOD′s function, its anti\|oxygen mechanism, types and production mode, etc., and also expounds the application situation and development potential of SOD in industries (pharmaceuticals, food and personal care products) and agriculture, so as to provide references for the further development and utilization of SOD products in China.

Key words: superoxide dismutase, reactive oxygen, radical, research progress

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