Journal of Agricultural Science and Technology ›› 2020, Vol. 22 ›› Issue (11): 63-68.DOI: 10.13304/j.nykjdb.2020.0643

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Research Progress of miRNA Regulating Residual Feed Intake of Livestock and Poultry

BAI Hao1 , YANG Baolong 2, DONG Zhaoqi 2, LI Xiaofan 2, JIANG Yong 2, CHANG Guobin 1,2, CHEN Guohong 1,2*   

  1. 1.Joint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education; Institutes of Agricultural Science and Technology Development, Yangzhou University, Jiangsu Yangzhou 225009, China;
    2.College of Animal Science and Technology, Yangzhou University, Jiangsu Yangzhou 225009, China
  • Received:2020-07-21 Online:2020-11-15 Published:2020-10-16

miRNA调控畜禽剩余采食量的研究进展

白皓1,杨宝龙2,董钊绮2,李潇凡2,江勇2,常国斌1,2,陈国宏1,2*   

  1. 1.扬州大学农业科技发展研究院, 教育部农业与农产品安全国际合作联合实验室, 江苏 扬州 225009;
    2.扬州大学动物科学与技术学院, 江苏 扬州 225009
  • 通讯作者: 陈国宏 E-mail: ghchen@yzu.edu.cn
  • 作者简介:白皓 E-mail: bhowen1027@yzu.edu.cn
  • 基金资助:
    国家自然科学基金青年基金项目(31902140);
    国家现代农业产业技术体系项目(CARS-42-3);
    江苏省农业科技自主创新资金项目(CX [18]1004)

Abstract: Residual feed intake (RFI) is an important evaluation index for feed efficiency of livestock and poultry. miRNAs are a class of endogenous non-coding single-strand RNA molecules with  length of around 22 nt, which are important regulators for gene expression. Previous studies revealed that miRNAs were closely related to feed intake and energy metabolism of animals, which participated in the regulation of RFI in cattle, pigs, chickens and other animals. This article summarized the research status of RFI, especially the research progress of miRNA regulating RFI of livestock and poultry in recent years, which would help to reveal the molecular regulation mechanism of RFI trait, provide new ideas for the improvement of feed efficiency and efficient production of livestock and poultry, and provide a theoretical basis for molecular breeding of the high-quality livestock and poultry.

Key words: livestock and poultry, feed efficiency, residual feed intake, miRNA

摘要: 剩余采食量(residual feed intake, RFI)是评价畜禽饲料利用率的重要指标。microRNA(miRNA)是一类通过转录后抑制基因表达的内源性非编码单链RNAs,长度约为22 nt,是基因表达的重要调控因子。miRNA与动物机体的采食及能量代谢密切相关,参与调控牛、猪、鸡等动物的RFI。针对近年来畜禽RFI的研究现状,特别是miRNA调控畜禽剩余采食量的研究进展进行总结,有助于揭示畜禽RFI性状的分子调控机理,为畜禽饲料利用率的改良与高效生产提供新思路,为优质畜禽的分子选育工作提供理论依据。

关键词: 畜禽, 饲料利用率, 剩余采食量, miRNA