Abstract: With the development of genetic engineering technology, the global planting areas for genetically modified (GM) crops are increasing sustainably. More than 75% of GM crops and their by-products are used as animal feed. It is very necessary to evaluate the safety of GM crops. Intestinal tract is the largest organ in immune system and plays an important role in maintening normal physiological functions of animals. Studies on unintended effects of GM crops on intestinal tract are the hot spots in safety assessment of GM crops as animal feed. This paper introduced the particularity and necessity of safety evaluation of GM crops as animal feed; analyzed the potential digestion and transfer rules of the transgenic ingredients in animal feed; and summarized the research progress on unintended effects of GM crops in intestinal morphology and microecology balance of the livestock and poultry, which was expected to provide references for the establishment and perfect of GM crops evaluation system.

Key words: genetically modified crops, livestock and poultry, intestinal microecology, safety evaluation, unintended effects

摘要： 随着基因工程技术的发展，全球转基因作物种植面积持续增加，转基因作物及其加工副产物75%以上用于动物饲料原料，因而，非常有必要开展转基因作物饲用安全性评价研究。肠道是机体最大的免疫器官，肠道健康对动物正常生理功能的维持具有重要作用，转基因作物对肠道的非预期效应研究是转基因作物饲用安全性评价的热点。介绍了转基因作物饲用安全性评价的特殊性与必要性，分析了饲料中转基因成分在体内的潜在消解和转移规律，综述了转基因作物对畜禽肠道形态结构和微生态平衡非预期效应的研究进展，旨在为转基因作物饲用安全性评价体系的建立与完善提供参考。

关键词: 转基因作物, 畜禽, 肠道微生态, 安全性评价, 非预期效应