›› 2015, Vol. 17 ›› Issue (3): 167-174.DOI: 10.13304/j.nykjdb.2014.540

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Research Status on Laccase-type Phenoloxidase in Marine Invertebrate

JIANG Jing-wei, DONG Ying, ZHOU Zun-chun*   

  1. (Liaoning Key Laboratory of Marine Fishery Molecular Biology, Liaoning Ocean and Fisheries Science Research Institute, Liaoning Dalian 116023, China)
  • Received:2014-09-11 Revised:2015-04-02 Online:2015-06-15 Published:2015-06-15

海洋无脊椎动物漆酶型酚氧化酶研究概况

蒋经伟,董颖,周遵春*   

  1. (辽宁省海洋水产科学研究院, 辽宁省海洋水产分子生物学重点实验室, 辽宁 大连 116023)
  • 通讯作者: 周遵春,研究员,博士,研究方向为海洋生物技术。E-mail:zunchunz@hotmail.com
  • 作者简介:蒋经伟|助理研究员|博士|研究方向为海洋动物免疫。E-mail:weijingjiang@live.cn。
  • 基金资助:

    国家自然科学基金项目(31402336);辽宁省科技计划项目(2014203006);辽宁省海洋与渔业厅项目(201301)资助。

Abstract:

Laccase-type phenoloxidase (PO) is an important component of innate defense system in some marine invertebrates. Laccase-type POs of marine invertebrates differ greatly from each other in evolutionary status,  structural characteristics, enzymatic characteristics, immune responsive characteristics, etc., suggesting that there might be differences in the immune and physiological functions of these enzymes. This paper summarized the laccase-type POs of marine invertebrate from the following aspects: discovery method, isozyme composition, molecular size, evolutionary status, structural characteristics, enzymatic characteristics and immune-responsive characteristics, etc., wishing to accumulate data for studying non-specific immunity of marine invertebrate.

Key words: marine invertebrate, laccase-type phenoloxidase, evolutionary status, structural characteristics, enzymatic characteristics, immune-responsive characteristics

摘要:

漆酶型酚氧化酶(PO)是一些海洋无脊椎动物非特异性免疫系统的重要组成因子。不同海洋无脊椎动物中的漆酶型PO在进化地位、结构特征、酶学特性和免疫应答特性等方面差异明显,表明不同漆酶型PO在免疫和生理功能上可能存在差异。从发现方法、同工酶组成、分子大小、进化地位、结构特征、酶学特性和免疫应答特性等几方面对海洋无脊椎动物漆酶型PO进行了综述,以期为海洋无脊椎动物非特异性免疫研究积累资料。

关键词: 海洋无脊椎动物;漆酶型酚氧化酶;进化地位;结构特征;酶学特性;免疫应答特性

CLC Number: