Research Progress on the Effects of Honey on Wound Healing and Its Mechanism

doi:10.13304/j.nykjdb.2019.0495

Journal of Agricultural Science and Technology ›› 2021, Vol. 23 ›› Issue (2): 123-133.DOI: 10.13304/j.nykjdb.2019.0495

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Research Progress on the Effects of Honey on Wound Healing and Its Mechanism

GUO Nana, ZHAO Yazhou, WANG Kai*, PENG Wenjun*

Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China

Received:2019-06-14 Online:2021-02-15 Published:2019-08-16

蜂蜜对创伤愈合的作用及机理研究进展

郭娜娜,赵亚周,王凯*,彭文君*

中国农业科学院蜜蜂研究所, 北京 100093

通讯作者: 王凯 E-mail: kaiwang628@gmail.com；彭文君 E-mail: pengwenjun@vip.sina.com
作者简介:郭娜娜 E-mail: 82101172145@caas.cn
基金资助:
国家自然科学基金项目（31702287）;
中国农业科学院科技创新工程项目(CAAS-ASTIP-2019-IAR)；

国家蜂产业技术体系项目（CARS-44）

Abstract

Abstract:

Honey has many biological activities, such as anti-bacterial, anti-oxidant and anti-inflammatory effects, especially in treating infectious wounds, burn burns, and

promoting wound healing properties. In this paper, the results of relevant cell studies, animal experiments and clinical trials of honey for the treatment of skin

trauma were analyzed and summarized. The clinical applications of honey and its mechanism of action of specific beneficial effects, including anti-bacterial,

antioxidant, anti-inflammatory, prevention of wound infection, promotion of self-dissolution debridement, stimulation of the growth of the wound granulation tissue, and acceleration of wound healing, were discussed in detail. The mechanism and clinical effect of honey on wound healing would provide a theoretical reference for the further development and utilization of honey.

Key words: honey, wound healing, mechanism of action, clinical treatment

摘要：

蜂蜜具有抗菌、抗氧化、抗炎等多种生物活性，特别是在治疗感染性创伤以及烧伤烫伤、促进伤口愈合等方面具有良好疗效。深入分析了蜂蜜治疗皮肤创伤相关的细胞实验、动物实验、临床试验的研究结果；详细论述了蜂蜜的临床应用及蜂蜜抗菌、抗氧化、抗炎、预防伤口感染、促进自溶清创、刺激创面肉芽组织生长、加速创面愈合的作用机理。蜂蜜对创伤愈合的作用机理及其临床效果将为蜂蜜的进一步开发利用提供理论参考。

关键词: 蜂蜜, 创伤愈合, 作用机制, 临床治疗

GUO Nana, ZHAO Yazhou, WANG Kai*, PENG Wenjun*. Research Progress on the Effects of Honey on Wound Healing and Its Mechanism[J]. Journal of Agricultural Science and Technology, 2021, 23(2): 123-133.

郭娜娜,赵亚周,王凯*,彭文君*. 蜂蜜对创伤愈合的作用及机理研究进展[J]. 中国农业科技导报, 2021, 23(2): 123-133.

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Research Progress on the Effects of Honey on Wound Healing and Its Mechanism

蜂蜜对创伤愈合的作用及机理研究进展

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