Abstract:

Aptamer is an oligonucleotide that can recognize specificity and bind to corresponding targets. It has strong affinity and is highly stable and easier to modify. It has been widely used in detection, separation and purification, medical treatment. The detection assay based on nucleic acid aptamer technology has developed rapidly, and been applied in detecting small molecule, protein, bacteria and viruses, etc.. This paper reviewed the research progress in detecting harmful substances in food by nucleic acid aptamer.

Key words: nucleic acid aptamer, detection, food, harmful substances

摘要：

核酸适配体是一段可以特异性识别并结合靶分子的寡聚核苷酸片段，具有亲和力强、稳定性好、易于修饰等特点，已经广泛用于检测、分离纯化和医疗三大领域。基于核酸适配体技术的检测方法得到了迅速地发展，已经应用于小分子、蛋白质、细菌病毒等方面的检测。主要综述了核酸适配体检测食品中有害物的研究进展。

关键词: 核酸适配体；检测；食品；有害物