›› 2012, Vol. 14 ›› Issue (5): 145-152.DOI: 10.3969/j.issn.10080864.2012.05.22

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Research Progress on Fish Genetically Engineered Vaccine

TIAN Yuanyuan, YE Xing*   

  1. Key Lab of Tropical &|Subtropical Fishery Resource Application &|Cultivation, Ministry of Agriculture|Pearl River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510380, China
  • Received:2012-05-02 Online:2012-10-15 Published:2012-10-15



  1. 中国水产科学研究院珠江水产研究所, 农业部热带亚热带水产资源利用与养殖重点实验室,  广州 510380
  • 通讯作者: 叶星,研究员,博士,博士生导师,主要从事水产生物技术研究。Email:gzyexing@163.com
  • 作者简介:田园园,助理研究员,硕士,主要从事水产生物技术研究。Email:tianyuan320@163.com
  • 基金资助:



At present, vaccination is the most costeffective way to control diseases in fish. The rapid development in immunology and bioengineering has greatly promoted the studies on genetically engineered vaccines for fish. It overcomes some defects and deficiencies of the traditional vaccines and shows great application prospect, and has become a research focus on aquaculture at home and abroad. This paper reviewed the present status and achievements gained in genetically engineered vaccine against fish pathogens, and problems encountered in commercialization of fishery genetically engineered vaccines that need to be solved urgently.

Key words: fish, genetically engineered vaccine, immunization pattern, DNA vaccines;subunit vaccines



关键词: 鱼;基因工程疫苗;免疫方式;DNA疫苗;亚单位疫苗

CLC Number: