›› 2008, Vol. 10 ›› Issue (1): 28-33.

• 综述 • 上一篇    下一篇

昆虫Bt作物抗性与中肠类钙粘蛋白的关系

张应[1,2] 梁革梅[1] 雷朝亮[2] 吴孔明[1]   

  1. [1]中国农业科学院植物保护研究所,植物病虫害生物学国家重点实验室,北京100094 [2]华中农业大学植物科技学院昆虫资源研究所,武汉430070
  • 收稿日期:2007-11-02 修回日期:2007-12-12 出版日期:2008-02-15 发布日期:2009-07-30
  • 通讯作者: 吴孔明,研究员,主要从事害虫防治研究。Tel:010-62815906;E-mail:kmwu@ippcaas.cn
  • 作者简介:张应|硕士研究生|主要从事害虫对Bt抗性治理研究。
  • 基金资助:

    国家973计划项目(2006CB102004)和国家自然科学基金项目(30771424)资助.

Relationship Between Insect Resistance to Bt Crops and |Cadherin-like Protein in Their Midgut

ZHANG Ying, LIANG Ge-mei| LEI Chao-liang, WU Kong-ming   

  1.  1. National Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100094|2. Institute of Insect Resources, College of Plant |Science and Technology, Huazhong Agricultural University, Wuhan 430070, China
  • Received:2007-11-02 Revised:2007-12-12 Online:2008-02-15 Published:2009-07-30

摘要:

Bt作物已在世界范围内广泛种植,为有效控制害虫的危害发挥了重要作用。靶标害虫的抗性问题是影响Bt作物长期利用的关键因素。通过分析Bt Cry1A毒素的主要受体类钙粘蛋白(cadherin-like)的生物学特性及其与Bt毒素的结合作用,讨论类钙粘蛋白基因突变与Bt抗性的关系,综述了基于基因突变的抗性分子检测技术的研究进展。

关键词: 类钙粘蛋白 Bt作物 受体 抗性治理 分子检测

Abstract:

Bt crops,one kinds of GM crops that express Cry1Ac or Cry1Ab protein have been commercialized worldwide. They are playing an important role in controlling insect pests. The issue of resistance evolution of the target pests is a key factor influencing the sustainable utilization of Bt crops. Through analyzing the biological characteristics of cadherin-like protein that is the main receptor of Bt Cry1A toxin, and its binding action  with Bt toxin, this paper discusses the relation between gene mutation and Bt resistance, and summarizes the research progress achieved in DNA-based approaches for molecular detection of insect resistance.

Key words: cadherin-like protein , Bt crop , acceptor, resistance management , molecular detection

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