Advances in Mechanism of Skeletal Muscle-adipose Crosstalk in Regulating Intramuscular Fat Depostion

doi:10.13304/j.nykjdb.2024.0158

Abstract

Abstract:

Muscle and adipose tissue are important components of the livestock organism， and they both act as endocrine organs to secrete cytokines， exosomes and other substances， and to regulate intramuscular fat deposition by autocrine and paracrine means. There are differences in intramuscular fat deposition among different varieties， strains， and even different individuals of the same strain. Intramuscular fat is closely related to meat quality and flavour. However， its deposition is influenced by genetic， environmental and nutritional level factors， and is also interconnected with muscle tissue. The development and type of muscle fiber and the number of myogenic cells also affect intramuscular fat deposition. Therefore， the recent research progress on skeletal muscle-adipose crosstalk mainly in terms of cytokines， exosomes， metabolites and the function of organelles were reviewed， which laid some foundation for genetic improvement of intramuscular fat and meat quality and flavor.

Key words: muscle, adipose tissue, intramuscular fat, cytokines, miRNA, metabolite

摘要：

肌肉和脂肪组织是畜禽机体的重要组成部分，二者都能作为内分泌器官分泌细胞因子、外泌体等物质，并通过自分泌和旁分泌方式调节肌内脂肪沉积。不同的品种、品系甚至同一品系不同个体间肌内脂肪的沉积均有差异。肌内脂肪与肉品质及风味密切相关，其沉积受遗传、环境和营养水平因素的影响，同时又与肌肉组织之间相互联系，如肌纤维发育和类型以及肌源性细胞的数量也会影响肌内脂肪沉积。因此，主要从细胞因子、外泌体、代谢产物和细胞器功能等方面综述肌肉与肌内脂肪互作的最新研究进展，为肌内脂肪和肉品质及风味的遗传改良奠定基础。

关键词: 肌肉, 脂肪组织, 肌内脂肪, 细胞因子, miRNA, 代谢产物

CLC Number:

Jiaqi YAO, Chunyan YANG, Yunfeng YANG, Hao BAI, Yong JIANG, Guobin CHANG, Guohong CHEN, Zhixiu WANG. Advances in Mechanism of Skeletal Muscle-adipose Crosstalk in Regulating Intramuscular Fat Depostion[J]. Journal of Agricultural Science and Technology, 2025, 27(9): 21-34.

姚佳琦, 杨春彦, 杨云凤, 白皓, 江勇, 常国斌, 陈国宏, 王志秀. 肌肉与脂肪组织互作调节肌内脂肪沉积的研究进展[J]. 中国农业科技导报, 2025, 27(9): 21-34.

Figures/Tables 2

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